Cinchonine: Bridging Traditional and Contemporary Therapies
Natural compounds have always played an important role in the context of active pharmaceutical ingredients that contribute to and create the framework of modern drugs. Natural product cinchonine is an important alkaloid and natural product obtained from cinchona trees. Today it is also very important in pharmaceuticals due to its history as well as modern pharmaceutical applications and is readily available to use cinchonine raw material and it has a solid value in global API. Historical importance of Cinchonine The history of Cinchonine originates from the cinchona tree which is native to South America. Local inhabitants used cinchona tree bark extract for the treatment of fevers and malaria; the practices then become the foundation for the modern drugs that cure malaria. It plays an equally important role together with quinine in early therapy. The story and utilization of cinchonine came to global prominence after 17 th and 18 th century when cinchona trees bark came to Europ...