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Lumefantrine USP: A Reliable API in Modern Malaria Treatment

  Malaria is one of the most difficult infectious diseases to control in many parts of the world. It particularly persists in tropical and sub-tropical areas. Despite increasing advances in general health provision many people still depend on powerful medicines to prevent or treat many infections, especially malaria. In an arena of ever evolving fight against this disease; Lumefantrine USP , a generic medicine, has established itself as a reliable pharmaceutical among the many antimalarial drugs available globally. As a safe, highly stable and effective active ingredient for antimalarial derivatives, it has become popular ingredient for antimalarial drug development worldwide. Pharmaceutical companies on various markets across the world still choose to source best quality lumefantrine API for their consistent patient results. Lumefantrine USP is normally linked with antimalarial artemisinin derivatives in combination drugs that offer better effectiveness and resistance controls. Th...

Quinidine Base: A Trusted API for Antiarrhythmic Therapies

  Cardiovascular diseases remain one of the most prevalent concerns in global health. This requires increased demand for safe, effective cardiac drugs. Among the plethora of formulations that have manifested over the years, quinidine base has proven to be an ever-reliable, evergreen component in the treatment of cardiac disturbances. Its reliability in therapeutic advances, reliability as an API, and consistent performance have demonstrated the tremendous utility of this compound when it comes to modern antiarrhythmic formulations. As the pharmaceutical standards become more rigid, this time-tested compound Indian origin is even more important as an API for pharmaceutical manufacturers in all global markets. The core of the matter is the fact that quinidine base itself is an antiarrhythmic API that is used for management of foetal arrhythmias including atrial fibrillation and ventricular arrhythmias. It helps in reducing electrical activity of the heart during atrial fibrillation....

Trusted Nicotine Sulphate API for Regulated Pharmaceutical Markets

  In current pharmaceutical industry environment, increased stability and reliability is essential for active ingredients and intermediates across regulated markets. The client expectations of high-quality performance therefore needs to be met by high-purity active pharma ingredients (API). The global rising healthcare standards now demand quality, safety, validation, compliance, availability, high performance coupled with high output capacity from pharmaceutical manufacturing companies. Nicine sulphate otBulk Drug is one such API which meets all the above expectations. Availability of certified and recognized nicotine sulphate is a typical example of regulated API performance. It finds its usage in numerous pharmaceutical formulations and therapies all over the world. As a drug molecule, nicotine sulphate has well-validated pharmacological properties making it suitable for various therapeutic uses. Manufacturing process is done under strict purity and stability controls to ensure...

Pharmaceutical Grade Nicotine Active Pharmaceutical Ingredients (APIs)

  Pharmaceutical Nicotine Active Pharmaceutical Ingredients (APIs) are important active substance platform in the regulated therapeutic areas. Nicotine is one of the examples where nicotine API with specific controlled released properties are widely used for pharma api applications. Among the types of nicotine tartrate API dihydrate, the pharmaceutical grade free acid form is most commonly used in pharma applications due to stability and suitable controlled release properties. This is considered as nicotine bitartrate salts suitable for pharma API manufacturing and application rather than the non-medicinal pharma applications. As the pharma regulatory norms are going, the requirements in nicotine active pharmaceutical ingredients manufacturing is increasing and this article highlights the role of pharma API including nicotine tartrate dihydrate in the pharma industry. What is Nicotine Tartrate Dihydrate? Nicotine tartrate dihydrate formulation or compound is obtained by combining ...

Nicotine EP and Its Role in Modern NRT Formulations

  Nicotine replacement therapy (NRT) remains a vital part of worldwide anti-smoking programs. At the heart of many NRT products is Nicotine EP ; a pharmacopeia grade product that fits the requirements of the European Pharmacopoeia. As regulations become stricter and quality expectations rise, companies working with regulated APIs need to understand the significance of Nicotine EP within pharmaceutical manufacturing. What is Nicotine EP? The phrase EU Nicotine EP active pharmaceutical ingredient (API) refers to nicotine that adheres to standards laid out in the European Pharmacopoeia, stipulating identity, purity, strength and limits for impurities. When used industrially or non-regulated, nicotine may not meet these high standards, but for use within the pharmaceutical field ( such as Nicotine EP active for use in pharmaceutical preparations) it must be manufactured to precise standards. Nicotine is a very powerful molecule and for this reason even minor deviations from high qualit...