prismIndustries

  Pharmaceutical Nicotine Active Pharmaceutical Ingredients (APIs) are important active substance platform in the regulated therapeutic areas. Nicotine is one of the examples where nicotine API with specific controlled released properties are widely used for pharma api applications. Among the types of nicotine tartrate API dihydrate, the pharmaceutical grade free acid form is most commonly used in pharma applications due to stability and suitable controlled release properties. This is considered as nicotine bitartrate salts suitable for pharma API manufacturing and application rather than the non-medicinal pharma applications. As the pharma regulatory norms are going, the requirements in nicotine active pharmaceutical ingredients manufacturing is increasing and this article highlights the role of pharma API including nicotine tartrate dihydrate in the pharma industry. What is Nicotine Tartrate Dihydrate? Nicotine tartrate dihydrate formulation or compound is obtained by combining ...

  Nicotine replacement therapy (NRT) remains a vital part of worldwide anti-smoking programs. At the heart of many NRT products is Nicotine EP ; a pharmacopeia grade product that fits the requirements of the European Pharmacopoeia. As regulations become stricter and quality expectations rise, companies working with regulated APIs need to understand the significance of Nicotine EP within pharmaceutical manufacturing. What is Nicotine EP? The phrase EU Nicotine EP active pharmaceutical ingredient (API) refers to nicotine that adheres to standards laid out in the European Pharmacopoeia, stipulating identity, purity, strength and limits for impurities. When used industrially or non-regulated, nicotine may not meet these high standards, but for use within the pharmaceutical field ( such as Nicotine EP active for use in pharmaceutical preparations) it must be manufactured to precise standards. Nicotine is a very powerful molecule and for this reason even minor deviations from high qualit...

  The pharma industry is constantly moving forward and demand for quality pharma active ingredients that are well regulated is ever increasing. In the midst of such demand, the pharma active that one simply cannot miss in the field of APIs is the nicotine alkaloid. The importance of pharmaceutical nicotine alkaloids in today's NRT (nicotine replacement therapy) and other regulated pharma applications cannot be over emphasized. If you are an api pharma company involved with nicotine derivative formulations, it is important for you to understand the source and the manufacturing process of nicotine alkaloids and the quality criteria involved in the manufacturing of such requirement. What is pharmaceutical nicotine alkaloid? Nicotine alkaloid is a naturally occurring organic compound predominantly found in tobacco plants. When used as an ingredient in pharma applications, the nicotine alkaloids are extracted, purified and refined in such a way that regulatory set parameters are not in...

  Cardiac rhythm disorders are a significant challenge in today’s healthcare landscape, and finding safe and effective pharmaceutical solutions is crucial. Among the treatments available, quinidine sulphate has gained a solid reputation for its effectiveness in managing irregular heart rhythms. Its reliable therapeutic results and consistent clinical outcomes make it a key player in cardiovascular drug formulations and a trusted choice in regulated pharmaceutical markets. Understanding Quinidine Sulphate Quinidine sulphate is an alkaloid-based compound that primarily serves as an antiarrhythmic agent. It helps regulate the heart's electrical conduction, aiding in the restoration and maintenance of a normal heart rhythm. Thanks to its predictable pharmacological effects, it’s commonly prescribed for conditions like atrial fibrillation and other rhythm irregularities. As a vital active pharmaceutical ingredient, quinidine sulphate must adhere to stringent quality, purity, and safety...

  In modern pharmaceutical therapy, antispasmodic drugs play a vital role in managing disorders related to smooth muscle spasms. Among these, hyoscyamine sulphate stands out as a well-established and effective compound. Derived from natural alkaloid sources, it has been widely used in gastrointestinal, urinary, and nervous system–related treatments. Its continued relevance highlights the importance of reliable hyoscyamine sulphate API production within today’s evolving pharmaceutical landscape. Understanding Hyoscyamine Sulphate Hyoscyamine sulphate is an anticholinergic agent known for its ability to reduce involuntary muscle contractions. By blocking the action of acetylcholine on smooth muscles, it helps relieve spasms, pain, and discomfort associated with various medical conditions. This mechanism makes it valuable in treating irritable bowel syndrome, peptic ulcers, bladder spasms, and certain neurological disorders. As one of the widely used pharmaceutical active ingredien...