Quality Quinine Dihydrochloride API by Prism Industries

 Introduction: The Importance of Quinine Dihydrochloride in Contemporary Medicine

Quinine Dihydrochloride API is a key ingredient in contemporary pharmaceuticals, particularly in the medication of malaria and other parasitic diseases. The centuries-old active ingredient, which is isolated from the bark of the cinchona tree, remains highly relevant in the field of healthcare.

We at Prism Industries Pvt. Ltd. are experts in the manufacture of high-purity Quinine Dihydrochloride API for pharmaceutical use. As a leading quinine dihydrochloride manufacturer, we ensure consistent, compliant, and effective API formulations. With an established reputation as one of the best API manufacturers in India, we supply products that conform to the highest standards worldwide.

This article dives deep into the uses, benefits, manufacturing processes, and global relevance of Quinine Di Hydrochloride, especially when sourced from a reputed bulk drugs manufacturer like Prism Industries.

What is Quinine Di Hydrochloride?

Understanding Quinine Di Hydrochloride

Quinine Di Hydrochloride is one form of quinine in salt form, commonly employed in injectable formulations for the management of severe malaria and leg cramps occurring at night. It is very soluble in water, which allows it to be used for intravenous injection. Being used as an API Bulk Drugs, it is extensively supplied to injectable and oral-based pharmaceutical manufacturing firms.

Major Properties of Quinine Di Hydrochloride

Molecular Formula: C20H24N2O2·2HCl

Molecular Weight: ~397.3 g/mol

Appearance: White or almost white crystalline powder

Solubility: Soluble in water and alcohol freely

Purity: ≥ 99% (according to pharmacopeial requirements)

Uses of Quinine Dihydrochloride API in Pharmaceuticals

1. Severe Malaria Treatment

Quinine Dihydrochloride API is usually applied in the management of malaria due to Plasmodium falciparum. It is effective in cases of resistance to other antimalarial agents. Intravenous products are administered when oral administration is not possible.

2. Treatment of Leg Cramps (off-label)

Though not suggested as a first-line therapy, Quinine Di Hydrochloride is sometimes employed for nocturnal leg cramp management in certain instances. Its relaxation effect on the muscles provides symptomatic relief to patients experiencing chronic cramping.

3. Veterinary Medicine Usage

Certain forms of quinine dihydrochloride API are also applied in veterinary applications for treating corresponding parasitic infections in animals.

Why Select Prism Industries as Your Manufacturer of Quinine Dihydrochloride

1. Unparalleled Purity and Quality Assurance

Being a GMP-certified company producing quinine dihydrochloride, Prism Industries Pvt. Ltd. puts every batch through stringent quality check. We adopt sophisticated analytical methods such as HPLC and GC to assure the purity and strength of our Quinine Dihydrochloride API. 

2. Global Regulatory Compliance

Our API Bulk Drugs adhere to market leading pharmacopeial standards like IP, BP, USP, and EP. We offer complete regulatory documentation such as Certificate of Analysis (CoA), Material Safety Data Sheets (MSDS), and GMP certification for hassle-free registration in overseas markets.

3. Bulk Supply and Custom Packaging

Being a well-established bulk drugs producer, we provide versatile packaging options for various client requirements. Whether you need kilo-lab scale material or complete commercial quantities, our manufacturing lines are capable of making timely shipments.

Process of Producing Quinine Dihydrochloride API

Step 1: Procurement of Natural Base

We start the process by procuring high-quality cinchona bark or a quinine-containing extract. The raw material is subjected to rigorous screening to achieve our in-house quality standards.

Step 2: Extraction and Purification

The quinine alkaloids are solvent-extracted, then crystallized and purified. Our method reduces impurities like cinchonine and other isomers.

Step 3: Conversion to Quinine Di Hydrochloride

The purified base is reacted with hydrochloric acid under controlled pH and temperature to form Quinine Di Hydrochloride. It is then crystallized, dried, and milled into powder.

Step 4: Final QC and Batch Release

Every batch of quinine dihydrochloride API is tested for:

Identity

Purity

Water content

Residual solvents

Microbiological limits

Only then is it released for packaging and distribution.

Certifications and Compliance

Being a leading API manufacturer in India, Prism Industries Pvt. Ltd. holds all key certifications such as:

WHO-GMP

ISO 9001:2015

FSSAI (for nutraceutical APIs)

Reach Compliance (for EU markets)

We provide our customers with complete regulatory dossiers and DMFs on request.

Why Quality Counts in Quinine Dihydrochloride API

Patient Safety

Impurities in antimalarial drugs may cause severe side effects. Our quality control ensures that our Quinine Dihydrochloride API is safe and effective.

Consistency in Formulation

APIs that differ in purity affect the formulation process. Our consistency enables pharmaceutical companies to keep their formulation standards without batch-to-batch differences.

Improved Market Acceptance

Pharmaceutical manufacturers prefer getting sourced from reputed quinine dihydrochloride suppliers such as Prism Industries as this facilitates faster approval from regulating authorities and good brand reputation. 

Packaging and Logistics

Customizable Safe Packaging

We package our Quinine Di Hydrochloride in HDPE barrels, fiber barrels, or individual vacuum-sealed foil packs containing nitrogen flush to provide maximum stability. 

Competitive Supply Chain

Being a global manufacturer of bulk drugs, we provide logistics assistance by air and sea with complete export documentation. Our robust distribution network provides timely delivery on continents.

Client Support and Technical Support

Dedicated Account Managers

Every client is provided with a technical and commercial account manager to facilitate smooth communication and project execution.

On-Demand Analytical Support

We give analytical method validation, stability data, and sample support on demand.

Market Demand and Global Outlook

1. Increasing Demand in Asia and Africa

High-burden countries are regularly importing quinine dihydrochloride API for national health schemes and private label products.

2. Government and NGO Orders

We work with NGOs and health ministries as a leading API manufacturer in India to provide quality APIs for mass drug administration.

3. Research and Development

Quinine Di Hydrochloride remains a subject of interest in pharma research owing to its antipyretic, anti-inflammatory, and antiviral uses.

Sustainability and Eco-Friendly Manufacturing

We are committed to green chemistry and waste reduction in our API manufacturing. Our ETP (Effluent Treatment Plant) ensures zero discharge, making us a responsible bulk drugs manufacturer in India.

Frequently Asked Questions (FAQs)

Q1: What makes Quinine Di Hydrochloride different from Quinine Sulphate?

A: Quinine Di Hydrochloride is more water-soluble, making it suitable for injectables, while quinine sulphate is used mostly in oral tablets.

Q2: Is Prism Industries API export certified?

A: Yes. We are GMP, ISO certified and possess all major documents for exporting API Bulk Drugs worldwide.

Q3: Do you supply small sample sizes for R&D?

A: Definitely. We supply R&D samples with complete CoAs and stability data as and when required.

Conclusion: Your Reliable Partner for Quality Quinine Dihydrochloride API

The pharmaceutical world requires purity, consistency, and regulatory compliance—and that is what Prism Industries Pvt. Ltd. provides. With a leading ranking as a manufacturer of quinine dihydrochloride and a bulk drug manufacturer, we don't just supply APIs; we provide confidence.

With our pure Quinine Dihydrochloride API, global access, and end-to-end client service, we are your best choice for sustainable and scalable pharmaceutical solutions. Whether you are formulating new drugs or want to enhance your existing supply chain, you can rely on us for uninterrupted delivery, impeccable quality, and technical superiority.

Select Prism Industries Pvt. Ltd.—a leading API manufacturer in India—for all your quinine dihydrochloride API and API bulk drugs requirements.