Hyoscyamine Hydro Bromide API: Quality Supply for Pharma Industry

 Introduction: The Importance of Hyoscyamine Hydro Bromide in Modern Medicine

In the ever-evolving world of pharmaceuticals, having effective and precise treatment options is essential for managing both chronic and acute conditions. One standout therapeutic compound is hyoscyamine hydro bromide, a potent anticholinergic that plays a crucial role in various drug formulations. This active pharmaceutical ingredient (API) is indispensable for treating gastrointestinal disorders, bladder spasms, symptoms related to Parkinson’s, and much more.

As the demand for high-quality, GMP-compliant hyoscyamine hydro bromide continues to rise, finding reliable and experienced suppliers becomes increasingly important. At Prism Industries Pvt. Ltd., we take pride in being a trusted supplier of hyoscyamine API to leading pharmaceutical brands around the globe, delivering top-notch pharma ingredients that adhere to strict international standards.

Understanding Hyoscyamine Hydro Bromide: What Makes It Effective

What is Hyoscyamine Hydro Bromide?

Hyoscyamine hydro bromide is a naturally occurring tropane alkaloid found in plants like belladonna and henbane. As an anticholinergic agent, it works by blocking the action of acetylcholine in the body, particularly affecting smooth muscles, secretory glands, and the central nervous system. This mechanism helps alleviate muscle spasms and reduce fluid secretions.

It's commonly used for:

- Irritable bowel syndrome (IBS)

- Peptic ulcers

- Urinary incontinence

- Parkinsonian tremors

- Motion sickness

Available in various forms such as tablets, liquids, and injections, hyoscyamine hydro bromide is a versatile and essential component in many treatment protocols.

Therapeutic Applications of Hyoscyamine Hydro Bromide

1. Gastrointestinal Disorders

Hyoscyamine hydro bromide is widely recognized for its effectiveness in treating gastrointestinal issues such as IBS and colitis. It works by relaxing the smooth muscles in the intestines, which helps alleviate cramps, pain, and irregular bowel movements.

2. Urinary Tract Relief

This medication is also beneficial for managing bladder spasms and the urgency to urinate, particularly in individuals dealing with neurogenic bladder or overactive bladder conditions.

3. Parkinson’s Disease

As a complementary treatment, hyoscyamine hydro bromide can assist in controlling tremors and muscle stiffness that often accompany Parkinson’s disease.

4. Respiratory and Secretory Control

In settings like palliative care or before surgery, hyoscyamine hydro bromide is utilized to minimize respiratory secretions, enhancing the comfort of patients.

Pharmacological Properties of Hyoscyamine Hydro Bromide

Action: Anticholinergic (muscarinic receptor antagonist)

Absorption: Quickly absorbed from the gastrointestinal tract

Onset of Action: 30 minutes to 1 hour

Duration: 4 to 6 hours

Formulations: Available in oral tablets, sublingual tablets, extended-release capsules, and injectable solutions

These pharmacological characteristics make hyoscyamine hydro bromide a reliable choice for both chronic and acute care situations.

Prism Industries Pvt. Ltd.: Your Go-To Supplier for Hyoscyamine API

As a top-notch manufacturer and exporter of pharmaceutical APIs, Prism Industries Pvt. Ltd., one of the active pharmaceutical ingredient manufacturers,  has earned a solid reputation as a trusted hyoscyamine API supplier across the globe. What sets us apart is:

- WHO-GMP-compliant facilities

- Rigorous quality control measures

- Tailored bulk order solutions

- Support with regulatory documentation for international compliance

By producing high-quality hyoscyamine hydro bromide, we make sure our clients get APIs that meet their formulation needs and adhere to regulatory standards.

The Manufacturing Process of Hyoscyamine Hydro Bromide

1. Alkaloid Extraction

We kick things off by extracting tropane alkaloids from natural sources like Atropa belladonna. These are meticulously processed to yield pure hyoscyamine.

2. Chemical Conversion

Next, we use bromide reaction processes to transform the extracted compound into hyoscyamine hydro bromide, maintaining its pharmacological properties while boosting stability and solubility.

3. Purification and Testing

We employ advanced purification techniques such as crystallization and solvent extraction to achieve pharmaceutical-grade purity. Each batch undergoes testing for:

- Potency and identity

- Impurities

- Residual solvents

- Microbial contamination

- Particle size distribution

4. Compliance and Certification

Our manufacturing processes adhere to global cGMP standards, ensuring that every shipment of hyoscyamine hydro bromide meets the requirements of international pharmacopoeias like IP, BP, and USP.

When it comes to choosing hyoscyamine hydro bromide from Prism Industries, here are some key benefits to consider:

1. Consistent Purity and Potency

We take quality seriously. Our hyoscyamine hydro bromide is rigorously tested to ensure it meets or even surpasses pharmacopoeial standards.

2. Comprehensive Regulatory Support

We’ve got you covered with all the necessary documentation, including:

- COA (Certificate of Analysis)

- DMF (Drug Master File)

- MSDS (Material Safety Data Sheet)

- Stability Data

3. Tailored Solutions and Bulk Supply

As a seasoned supplier of hyoscyamine API, we’re equipped to handle everything from small-scale R&D projects to large commercial orders.

4. Global Logistics Expertise

Our well-established supply chain guarantees that we can deliver to clients in Europe, North America, Asia, and Africa on time, every time.

The global demand for hyoscyamine hydro bromide is on a steady rise, driven by several key factors:

- An increase in gastrointestinal disorders

- A growing elderly population

- Greater awareness surrounding palliative care medications

- A spike in neurodegenerative diseases like Parkinson’s

As regulations tighten, pharmaceutical companies are on the lookout for dependable suppliers of hyoscyamine APIs who can consistently deliver high-quality products, batch after batch.

**Product Specifications at a Glance**

- **Parameter:** Specification

- **Product Name:** Hyoscyamine Hydro Bromide

- **CAS Number:** 6020-87-7

- **Molecular Formula:** C17H23NO3·HBr

- **Appearance:** White to off-white crystalline powder

- **Assay:** NLT 98%

- **Solubility:** Freely soluble in water and alcohol

- **Shelf Life:** 3 years (when stored in original packaging)

- **Storage:** Keep in cool, dry conditions

**Formulation Options Using Hyoscyamine Hydro Bromide**

- **Oral Tablets:** Ideal for IBS and colitis

- **Sublingual Tablets:** Quick relief for spasmodic pain

- **Extended-Release Capsules:** Long-lasting effects for chronic conditions

- **Injectables:** Used in hospitals and emergency care

- **Liquid Oral Solutions:** Suitable for pediatric and geriatric patients

FAQs: Hyoscyamine Hydro Bromide

1. How does hyoscyamine hydro bromide differ from atropine or scopolamine?

While all three belong to the anticholinergic alkaloid family, hyoscyamine hydro bromide is known for its more focused impact on the gastrointestinal tract, resulting in fewer side effects related to the central nervous system.

2. Will I receive a COA and DMF with my order?

Absolutely! As your supplier of hyoscyamine API, we ensure you receive all necessary documentation, including the Certificate of Analysis (COA) and Drug Master File (DMF).

3. Is it safe to use for an extended period?

When used under medical supervision, hyoscyamine hydro bromide is generally regarded as safe for long-term treatment, particularly for chronic gastrointestinal issues.

4. Do you ship this API worldwide?

Yes, we collaborate with logistics partners to guarantee prompt international deliveries, complete with all required regulatory documentation.

5. Is this API available in different grades?

We offer hyoscyamine hydro bromide in various grades, including IP, BP, and USP, to meet diverse formulation needs.

Conclusion: Partner with Prism Industries for Quality Hyoscyamine Hydro Bromide API

The need for dependable and effective pharmaceutical ingredients like hyoscyamine hydro bromide is on the rise. With its wide range of applications, strong safety profile, and established therapeutic benefits, this API plays a crucial role in many treatment areas.

At Prism Industries Pvt. Ltd., we are dedicated to supporting global healthcare brands by providing pharmaceutical-grade hyoscyamine hydro bromide, ensuring quality, consistency, and thorough documentation. As a reliable hyoscyamine API supplier, we strive to deliver safe and effective formulations to patients around the world.

Choose Prism Industries Pvt. Ltd.—where innovation and quality come together to provide trusted pharmaceutical ingredients for a healthier future.